Endocrine Abstracts

Background: Patients with acromegaly have an increased risk of vertebral fractures, yet normal or elevated bone mineral density (BMD) by dual-energy X-ray absorptiometry (DXA). This suggests that DXA may not be a reliable tool for assessing BMD in acromegalic patients. Multiple studies have suggested that patients with acromegaly have compromised trabecular bone but not cortical bone. Quantitative computed tomography (QCT) represents a three-dimensional technique for quantifyi...

Objective: Studies have demonstrated that patients with acromegaly have compromised bone health and an increased risk of vertebral fractures (VFs). However, the prevalence of VFs in Chinese patients with acromegaly has not been investigated by far. This study aimed to evaluate the prevalence and determinants of VFs in patients with acromegaly in a tertiary hospital in China.Methods: We enrolled patients diagnosed with acromegaly consecutively at West Chi...